Inflammation of a Posterior Ciliary Artery in a Naive Cynomolgus Macaque

Toxicol Pathol. 2021 Apr;49(3):602-604. doi: 10.1177/0192623320952337. Epub 2020 Aug 28.

Abstract

This brief communication describes a previously unreported background lesion in the eye of a naive cynomolgus macaque. Inflammation of a posterior ciliary artery was, in this case, morphologically similar to vascular inflammation of other tissues described in naive cynomolgus macaques. However, the available literature does not describe this lesion at this anatomical site. The affected animal did not present with any abnormal clinical signs and ophthalmological examinations were within normal limits. Toxicologic pathologists should be aware of this finding in order to help differentiate it from a test item-related finding.

Keywords: background lesions; cardiovascular system; nonhuman primate pathology; vascular system.

MeSH terms

  • Animals
  • Ciliary Arteries*
  • Humans
  • Inflammation* / veterinary
  • Macaca fascicularis