This study explored the fate of Zn- resistance genes (ZRGs), antibiotic- resistance genes (ARGs) and related mechanisms associated with bacterial communities during co-composting of erythromycin manufacturing wastes (EMW) and pig manure (PM) at the ratio of 0% (control), 5% (L) and 20% (H) (PM basis). The relative abundance (RAs) of erm genes in most treatments were decreased by 77.75-99.97% after composting. But total RA of czc genes were increased by 8.34, 15.86 and 12.03 times in control, L and H treatment respectively. The higher EMW in H showed a negative impact on removing of erm genes and aggravated the enrichment of ZRGs compared with control and L. Redundancy analysis showed that Firmicutes accounted for the highest explanation of ARGs and ZRGs variations, and Zn in EMW had significant impact on the succession of bacterial community.
Keywords: Antibiotic resistance genes; Bacterial community; Co-composting; Erythromycin manufacturing wastes; Zinc resistance genes.
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