Vancomycin AUC-guided therapeutic drug monitoring to reduce nephrotoxicity: are we overlooking a simpler solution? Comment on: Oda K, Jono H, Nosaka K, Saito H. Reduced nephrotoxicity in vancomycin therapeutic drug monitoring guided by area under the concentration-time curve against trough 15-20 µg/mL concentration

Int J Antimicrob Agents. 2020 Nov;56(5):106150. doi: 10.1016/j.ijantimicag.2020.106150. Epub 2020 Aug 31.
No abstract available

Publication types

  • Letter

MeSH terms

  • Anti-Bacterial Agents / adverse effects*
  • Anti-Bacterial Agents / therapeutic use
  • Area Under Curve
  • Drug Monitoring / methods*
  • Humans
  • Kidney / drug effects*
  • Microbial Sensitivity Tests
  • Renal Insufficiency / chemically induced*
  • Renal Insufficiency / prevention & control
  • Vancomycin / adverse effects*
  • Vancomycin / therapeutic use

Substances

  • Anti-Bacterial Agents
  • Vancomycin