Mechanism of inhibition of prostacyclin synthesis by cyclosporine in cultured human umbilical vein endothelial cells

Transplant Proc. 1988 Jun;20(3 Suppl 3):654-7.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cyclosporins / pharmacology*
  • Cytochrome P-450 Enzyme Inhibitors
  • Cytochrome P-450 Enzyme System
  • Endothelium, Vascular / drug effects*
  • Epoprostenol / biosynthesis*
  • Humans
  • In Vitro Techniques
  • Indomethacin / pharmacology
  • Intramolecular Oxidoreductases*
  • Isomerases / antagonists & inhibitors
  • Protein Biosynthesis
  • Thrombin / pharmacology

Substances

  • Cyclosporins
  • Cytochrome P-450 Enzyme Inhibitors
  • Cytochrome P-450 Enzyme System
  • Epoprostenol
  • Thrombin
  • Isomerases
  • Intramolecular Oxidoreductases
  • prostacyclin synthetase
  • Indomethacin