Future developments in biosensors for field-ready SARS-CoV-2 virus diagnostics

Biotechnol Appl Biochem. 2021 Aug;68(4):695-699. doi: 10.1002/bab.2033. Epub 2020 Oct 19.

Abstract

According to the evidence, the coronavirus disease 19 (COVID-19) is caused by a zoonotic pathogen named respiratory syndrome coronavirus 2 (SARS-CoV-2). This virus can spread through personal contact, respiratory droplets, and also through airborne transmission. A rapid, low-cost, and effective biosensor platform is essential to diagnose patients with COVID-19 infection, predominantly the asymptomatic individuals, and prevent the spread of the SARS-CoV-2 via transmission routes. The objective of this review is to provide a comparative view among current diagnostic methods, focusing on recently suggested biosensors for the detection of SARS-CoV2 in clinical samples. A capable SARS-CoV-2 biosensor can be designed by the holistic insights of various biosensor studies.

Keywords: COVID-19; SARS-CoV-2; biosensor; coronavirus; real-time PCR; serological assays.

Publication types

  • Review

MeSH terms

  • Biosensing Techniques* / instrumentation
  • Biosensing Techniques* / methods
  • COVID-19 Testing / instrumentation
  • COVID-19 Testing / methods
  • COVID-19* / diagnosis
  • COVID-19* / virology
  • Humans
  • SARS-CoV-2* / isolation & purification