Safety Assessment of 2-Amino-3-Hydroxypyridine as Used in Cosmetics

Int J Toxicol. 2020 Sep;39(2_suppl):91S-97S. doi: 10.1177/1091581820952376.

Abstract

The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of 2-Amino-3-Hydroxypyridine, which is reported to function as an oxidative hair dye ingredient. The Panel reviewed relevant animal and human data provided in this safety assessment, and concluded that 2-Amino-3-Hydroxypyridine is safe in the present practices of use and concentration for use in oxidative hair dye formulations.

Keywords: 2-Amino-3-Hydroxypyridine; cosmetics; safety.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Aminopyridines / chemistry
  • Aminopyridines / pharmacokinetics
  • Aminopyridines / toxicity*
  • Animals
  • Consumer Product Safety
  • Hair Dyes / chemistry
  • Hair Dyes / pharmacokinetics
  • Hair Dyes / toxicity*
  • Humans
  • Neoplasms / epidemiology
  • Risk Assessment
  • Toxicity Tests

Substances

  • Aminopyridines
  • Hair Dyes
  • 2-amino-3-hydroxypyridine