Mobile App Based Strategy Improves Door-to-Needle Time in the Treatment of Acute Ischemic Stroke

J Stroke Cerebrovasc Dis. 2020 Dec;29(12):105319. doi: 10.1016/j.jstrokecerebrovasdis.2020.105319. Epub 2020 Sep 23.

Abstract

Background: Time to revascularization is critical in improving outcomes in stroke thrombolysis. We studied the effectiveness of a mobile app based strategy to improve door-to-needle time (DNT) in treatment of acute ischemic stroke.

Methods: Consecutive patients presenting with acute ischemic stroke to the emergency department at a tertiary care hospital in Southern India between April 2017 - September 2018 were included. The app enabled rapid entry of patient parameters, the NIH stroke scale (NIHSS), thrombolysis checklist and dose calculation along with team synchronization, notifying all on-call members and team leaders of the patient movement, and sharing of radiological images. DNT captured from the app was compared to previous values from our center using one-way Analysis of Variance (ANOVA) after adjusting for differences in baseline variables.

Results: A total of 76 patients were thrombolysed during the study period, while using the mobile app. The mean DNT was 41 min, with 89% being thrombolysed within 60 min and 57% being thrombolysed within 45 min. Compared to 100 consecutive patients thrombolysed in the months prior to April 2017 where the mean DNT was 57 min, with 67% thrombolysed within 60 min and 47% being thrombolysed within 45 min, there was a mean DNT decrease of 16 min with 1.3x increase in DNT < 60 min. This difference was statistically significant after adjusting for age, sex and NIHSS Score (p=0.005, One-Way ANOVA).

Conclusion: We have been able to demonstrate a significant improvement in DNT using mobile app as a tool to improve team performance.

Keywords: Cerebral infarction; Door-to-needle time; Mobile application; Thrombolysis.

MeSH terms

  • Adult
  • Aged
  • Brain Ischemia / diagnosis
  • Brain Ischemia / drug therapy*
  • Delivery of Health Care, Integrated / organization & administration*
  • Emergency Service, Hospital / organization & administration*
  • Female
  • Fibrinolytic Agents / administration & dosage*
  • Humans
  • India
  • Interdisciplinary Communication
  • Male
  • Middle Aged
  • Mobile Applications*
  • Patient Care Team / organization & administration
  • Quality Improvement / organization & administration
  • Quality Indicators, Health Care / organization & administration
  • Stroke / diagnosis
  • Stroke / drug therapy*
  • Thrombolytic Therapy*
  • Time Factors
  • Time-to-Treatment / organization & administration*
  • Treatment Outcome

Substances

  • Fibrinolytic Agents