Instability of sputum molecular phenotypes in U-BIOPRED severe asthma

Eur Respir J. 2021 Feb 4;57(2):2001836. doi: 10.1183/13993003.01836-2020. Print 2021 Feb.

Abstract

At 1 year, 45% of severe asthma change molecular phenotype as determined by sputum transcriptomic analysis. Together with concomitant shift in sputum granulocytic markers, this may indicate variability of driving mechanisms in this unstable group. https://bit.ly/35aj489

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Asthma*
  • Eosinophils
  • Humans
  • Phenotype
  • Sputum*