Clinical, radiology, pathologic patterns and outcomes of vaping related pulmonary injury in a single institution; A case series

Maryam Kaous; Jonathan Xian; Daniel Rongo; Michelle McDonald; Daniel Ocasionez; Reeba Mathew; Rosa M Estrada-Y-Martin; Bela Patel; Sujith V Cherian; Pushan P Jani

doi:10.1016/j.rmed.2020.106153

Clinical, radiology, pathologic patterns and outcomes of vaping related pulmonary injury in a single institution; A case series

Respir Med. 2020 Nov:173:106153. doi: 10.1016/j.rmed.2020.106153. Epub 2020 Sep 20.

Authors

Affiliations

¹ Divisions of Pulmonary, Critical Care and Sleep Medicine University of Texas Health- McGovern Medical School, TX, 77030, USA. Electronic address: [email protected].
² Divisions of Pulmonary, Critical Care and Sleep Medicine University of Texas Health- McGovern Medical School, TX, 77030, USA. Electronic address: [email protected].
³ Department of Internal Medicine University of Texas Health- McGovern Medical School, TX, 77030, USA. Electronic address: [email protected].
⁴ Department of Pathology and Laboratory Medicine University of Texas Health- McGovern Medical School, TX, 77030, USA. Electronic address: [email protected].
⁵ Department of Radiology University of Texas Health- McGovern Medical School, TX, 77030, USA. Electronic address: [email protected].
⁶ Divisions of Pulmonary, Critical Care and Sleep Medicine University of Texas Health- McGovern Medical School, TX, 77030, USA. Electronic address: [email protected].
⁷ Divisions of Pulmonary, Critical Care and Sleep Medicine University of Texas Health- McGovern Medical School, TX, 77030, USA. Electronic address: [email protected].
⁸ Divisions of Pulmonary, Critical Care and Sleep Medicine University of Texas Health- McGovern Medical School, TX, 77030, USA. Electronic address: [email protected].
⁹ Divisions of Pulmonary, Critical Care and Sleep Medicine University of Texas Health- McGovern Medical School, TX, 77030, USA. Electronic address: [email protected].
¹⁰ Divisions of Pulmonary, Critical Care and Sleep Medicine University of Texas Health- McGovern Medical School, TX, 77030, USA. Electronic address: [email protected].

PMID: 33017782
DOI: 10.1016/j.rmed.2020.106153

Abstract

Since March 2019, E-cigarette or Vaping product associated lung injury (EVALI) has become an ongoing epidemic with more 2600 cases reported in the span of a few months in the United States. EVALI is defined as acute lung injury that develops secondary to the use of e-cigarettes or vaping products within the previous 90 days after exlusion of other possible inciting factors. Vitamin E acetate is believed to play a significant role in its pathogenesis. Treatment involves use of corticosteroids and further avoidance of these products. We describe a case series of 8 patients with EVALI, their clinical course and outcomes. All patients showed an excellent response to corticosteroids. In our experience, prognosis of EVALI is excellent, with complete resolution of symptoms in patients who followed up at 8 weeks.

Keywords: EVALI.

MeSH terms

Acute Lung Injury / diagnostic imaging
Acute Lung Injury / drug therapy*
Acute Lung Injury / etiology*
Adrenal Cortex Hormones / therapeutic use*
Adult
E-Cigarette Vapor / adverse effects*
Female
Follow-Up Studies
Humans
Lung Injury / diagnostic imaging*
Lung Injury / drug therapy
Lung Injury / etiology*
Male
Radiography, Thoracic
Tomography, X-Ray Computed
Treatment Outcome
Vaping / adverse effects*
Vitamin E / adverse effects
Young Adult

Substances

Adrenal Cortex Hormones
E-Cigarette Vapor
Vitamin E