An integrated peach genome structural variation map uncovers genes associated with fruit traits

Genome Biol. 2020 Oct 6;21(1):258. doi: 10.1186/s13059-020-02169-y.

Abstract

Background: Genome structural variations (SVs) have been associated with key traits in a wide range of agronomically important species; however, SV profiles of peach and their functional impacts remain largely unexplored.

Results: Here, we present an integrated map of 202,273 SVs from 336 peach genomes. A substantial number of SVs have been selected during peach domestication and improvement, which together affect 2268 genes. Genome-wide association studies of 26 agronomic traits using these SVs identify a number of candidate causal variants. A 9-bp insertion in Prupe.4G186800, which encodes a NAC transcription factor, is shown to be associated with early fruit maturity, and a 487-bp deletion in the promoter of PpMYB10.1 is associated with flesh color around the stone. In addition, a 1.67 Mb inversion is highly associated with fruit shape, and a gene adjacent to the inversion breakpoint, PpOFP1, regulates flat shape formation.

Conclusions: The integrated peach SV map and the identified candidate genes and variants represent valuable resources for future genomic research and breeding in peach.

Keywords: Fruit; Fruit shape; GWAS; Peach; SVs.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Anthocyanins / metabolism
  • Fruit / genetics*
  • Fruit / growth & development
  • Fruit / metabolism
  • Genome, Plant*
  • Genomic Structural Variation*
  • Prunus persica / genetics*

Substances

  • Anthocyanins