Mining the Antibody Repertoire for Solutions to SARS-CoV-2

Cell Host Microbe. 2020 Oct 7;28(4):499-501. doi: 10.1016/j.chom.2020.09.010.

Abstract

In this issue of Cell Host & Microbe, Nielsen and colleagues sequence antibody repertoires of patients with severe COVID-19 to reveal potentially convergent features on the background of a larger, polyclonal response. Their findings suggest that, as databases improve, it may be possible to monitor virus-specific B cells after infection or vaccination using antibody sequencing.

Publication types

  • Comment

MeSH terms

  • Antibodies, Viral
  • Antibody Formation
  • B-Lymphocytes
  • Betacoronavirus
  • COVID-19
  • Coronavirus Infections*
  • Humans
  • Immunoglobulin G
  • Pandemics*
  • Pneumonia, Viral*
  • SARS-CoV-2
  • Severe Acute Respiratory Syndrome*

Substances

  • Antibodies, Viral
  • Immunoglobulin G