Neurotoxicology: Clinical Approach and Causal Inference

Mam Ibraheem; Dong Y Han; Michael R Dobbs

doi:10.1016/j.ncl.2020.06.001

Neurotoxicology: Clinical Approach and Causal Inference

Neurol Clin. 2020 Nov;38(4):737-748. doi: 10.1016/j.ncl.2020.06.001.

Authors

Mam Ibraheem¹, Dong Y Han², Michael R Dobbs³

Affiliations

¹ Department of Neurology, University of Kentucky, 740 South Limestone, KY Clinic, J401, Lexington, KY 40536, USA; US Department of Veterans Affairs, Lexington VA Medical Center, Troy Bowling Campus, 1101 Veterans Drive, Room A303a, Mail Code: 127-CD, Lexington, KY 40502, USA. Electronic address: [email protected].
² Department of Neurology, University of Kentucky, 740 South Limestone, KY Clinic, J401, Lexington, KY 40536, USA; Department of Neurosurgery, University of Kentucky College of Medicine, Lexington, KY, USA; Department of Physical Medicine and Rehabilitation, University of Kentucky College of Medicine, Lexington, KY, USA.
³ Department of Neurology, University of Texas Rio Grande Valley School of Medicine, 2102 Treasure Hills, Harlingen, TX 78550, USA.

PMID: 33040858
DOI: 10.1016/j.ncl.2020.06.001

Abstract

Clinical neurotoxicology is an unrecognized neurologic subspecialty. Few neurology residency programs offer an organized education or training in the field. Nevertheless, neurotoxic exposures and subsequent injuries are common. This article provides a basic approach to clinical assessment and causal inference. It addresses the knowledge gap for clinical practice and provides a thematic structure to use interdisciplinary resources.

Keywords: Causality; Epidemiology; Evidence-based toxicology; Neurology; Toxicology.

Publication types

Review

MeSH terms

Causality*
Humans
Neurology / methods
Neurotoxicity Syndromes / diagnosis*