ASXL1 mutation confers poor prognosis in primary myelofibrosis patients with low JAK2V617F allele burden but not in those with high allele burden

Blood Cancer J. 2020 Oct 12;10(10):99. doi: 10.1038/s41408-020-00364-5.
No abstract available

Publication types

  • Clinical Trial
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Alleles
  • Amino Acid Substitution
  • Disease-Free Survival
  • Female
  • Humans
  • Janus Kinase 2 / genetics*
  • Male
  • Middle Aged
  • Mutation, Missense*
  • Primary Myelofibrosis* / genetics
  • Primary Myelofibrosis* / mortality
  • Repressor Proteins / genetics*
  • Retrospective Studies
  • Survival Rate

Substances

  • ASXL1 protein, human
  • Repressor Proteins
  • JAK2 protein, human
  • Janus Kinase 2