Magnetic Resonance Spectroscopy of γ-Aminobutyric Acid and Glutamate Concentrations in Children With Attention-Deficit/Hyperactivity Disorder

JAMA Netw Open. 2020 Oct 1;3(10):e2020973. doi: 10.1001/jamanetworkopen.2020.20973.

Abstract

This cohort study assesses concentrations of γ-aminobutyric acid (GABA) and glutamate in children with attention-deficit/hyperactivity disorder (ADHD) compared with typically developing children.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adolescent Development
  • Attention Deficit Disorder with Hyperactivity / diagnostic imaging*
  • Attention Deficit Disorder with Hyperactivity / metabolism*
  • Brain / diagnostic imaging*
  • Brain / metabolism*
  • Brain Mapping / methods
  • Case-Control Studies
  • Child
  • Cohort Studies
  • Frontal Lobe / diagnostic imaging
  • Frontal Lobe / metabolism
  • Glutamine / metabolism*
  • Gray Matter / diagnostic imaging
  • Gray Matter / metabolism
  • Gyrus Cinguli / diagnostic imaging
  • Gyrus Cinguli / metabolism
  • Humans
  • Image Processing, Computer-Assisted
  • Magnetic Resonance Spectroscopy
  • Temporal Lobe / diagnostic imaging
  • Temporal Lobe / metabolism
  • gamma-Aminobutyric Acid / metabolism*

Substances

  • Glutamine
  • gamma-Aminobutyric Acid