Management of visceral vascular anomalies

Semin Pediatr Surg. 2020 Oct;29(5):150977. doi: 10.1016/j.sempedsurg.2020.150977. Epub 2020 Sep 16.

Abstract

Visceral vascular anomalies are common in patients with vascular malformations in other parts of the body and can include lymphatic, venous, and arteriovenous malformations. Depending on the organ or organs involved they may present differently and pose different treatment challenges. Defining the malformation and understanding its extent is paramount in devising management regimens. Medical, interventional, and surgical therapies are often required in combination to treat these complex lesions. There are new and promising advances in the development of therapeutic agents targeting the PI3K/AKT/mTOR pathway. Due to the complex nature of these lesions a coordinated, multi-disciplinary approach is necessary to manage and mitigate symptoms and complications of this diverse group of vascular malformations.

Keywords: Vascular anomalies; Vascular malformations; Visceral.

Publication types

  • Review

MeSH terms

  • Arteriovenous Malformations* / diagnosis
  • Arteriovenous Malformations* / pathology
  • Arteriovenous Malformations* / therapy
  • Child
  • Chylothorax* / diagnosis
  • Chylothorax* / pathology
  • Chylothorax* / therapy
  • Gastrointestinal Neoplasms* / diagnosis
  • Gastrointestinal Neoplasms* / pathology
  • Gastrointestinal Neoplasms* / therapy
  • Humans
  • Lymphangiectasis* / diagnosis
  • Lymphangiectasis* / pathology
  • Lymphangiectasis* / therapy
  • Lymphatic Abnormalities* / diagnosis
  • Lymphatic Abnormalities* / pathology
  • Lymphatic Abnormalities* / therapy
  • Nevus, Blue* / diagnosis
  • Nevus, Blue* / pathology
  • Nevus, Blue* / therapy
  • Skin Neoplasms* / diagnosis
  • Skin Neoplasms* / pathology
  • Skin Neoplasms* / therapy
  • Vascular Malformations* / diagnosis
  • Vascular Malformations* / pathology
  • Vascular Malformations* / therapy
  • Viscera / pathology*

Supplementary concepts

  • Blue rubber bleb nevus syndrome