Aims: To assess the prevalence and associated factors of psychological distress among patients with chronic hepatitis B receiving oral antiviral therapy and explore the association between psychological distress and self-management behaviours among this population.
Design: A cross-sectional study.
Methods: A convenience sample of 188 patients with chronic hepatitis B receiving oral antiviral therapy was recruited from March-October 2018 to complete a self-report questionnaire including the Chinese version of Depression Anxiety Stress Scale-21 and Chronic Hepatitis B Self-Management Scale. Logistic regression analysis and hierarchical multiple regression analysis were used to determine the factors associated with psychological distress and the association between psychological distress and self-management behaviours respectively.
Results: The prevalence of depression, anxiety, and stress symptoms were 33.0%, 38.3% and 17.6% respectively. Depression was associated with older age, female gender, lower education level and longer treatment duration; anxiety was associated with female gender and longer treatment duration; and stress was associated with age of 31-40 years, female gender and unmarried status. There were significant associations between depression and anxiety symptoms and self-management behaviours.
Conclusion: Psychological distress was prevalent among patients with chronic hepatitis B receiving oral antiviral therapy and had a negative impact on self-management. Interventions targeting depression and anxiety symptoms may be beneficial to improve self-management behaviours for this population.
Impact: This study explored the factors associated with psychological distress in patients with chronic hepatitis B receiving oral antiviral therapy. The findings showed psychological distress was more common in patients who were with older age, female, less educated, unmarried and receiving longer duration of treatment and psychological distress was significantly associated with self-management behaviours. Nurses and other healthcare providers should provide interventions to reduce the risk of psychological distress and improve self-management behaviours for this population.
目标: 探讨慢性乙型肝炎患者接受口服抗病毒治疗后心理困扰的发生率及相关因素,以及研究这一群体中心理困扰与自我管理行为的关系。 设计: 横断面研究。 方法: 从2018年3月至10月,我们以188名接受口服抗病毒治疗的慢性乙型肝炎患者作为便利样本,完成一份自我报告问卷调查,包括中文版抑郁、焦虑和压力量表DASS-21和慢性乙型肝炎自我管理量表。采用逻辑回归分析和等级回归分析分别确定心理困扰的相关因素以及心理困扰与自我管理行为之间的关系。 结果: 抑郁、焦虑和应激症状的患病率分别为33.0%、38.3%和17.6%。抑郁的相关因素包括年龄大、女性、受教育程度低和治疗时间长;焦虑的相关因素包括女性和治疗时间长;压力的相关因素包括31岁至40岁、女性和未婚状态。抑郁和焦虑症状与自我管理行为之间存在显著关联性。 结论: 慢性乙型肝炎患者在接受口服抗病毒治疗时普遍存在心理困扰,并对自我管理有着消极的影响作用。针对抑郁和焦虑症状的干预措施可能有助于改善该群体的自我管理行为。 影响: 本研究探讨慢性乙型肝炎患者接受口服抗病毒治疗时的相关心理困扰因素。研究结果显示,心理困扰在年龄偏大、女性、受教育程度低、未婚且接受治疗时间较长的患者中更为常见,且心理困扰与自我管理行为具有显著相关性。护士和其他保健服务提供者应提供干预措施,以降低心理困扰的风险,并改善该群体的自我管理行为。.
Keywords: antiviral therapy; anxiety; chronic hepatitis B; depression; nursing; psychological distress; self-care; self-management behaviours; stress.
© 2020 John Wiley & Sons Ltd.