Erythrocyte hemighosts in a patient with tumor lysis syndrome: One train may hide another

Pierre Cabantous; Sylvie Daliphard; Victor Bobée

doi:10.1002/ccr3.3011

Erythrocyte hemighosts in a patient with tumor lysis syndrome: One train may hide another

Clin Case Rep. 2020 Jul 7;8(10):2069-2070. doi: 10.1002/ccr3.3011. eCollection 2020 Oct.

Authors

Pierre Cabantous¹, Sylvie Daliphard¹, Victor Bobée¹

Affiliation

¹ Department of Biological Hematology Rouen University Hospital Rouen France.

Abstract

Rasburicase was introduced to treat hyperuricemia secondary to tumor lysis syndrome. Because of severe hemolytic anemia, a blood smear was requested and showed hemighosts, revealing G6PD deficiency. Erythrocyte morphology is a key tool in laboratory hematology.

Keywords: G6PD deficiency; hematology; hemolytic anemia; methemoglobin; venetoclax.