Oxygen gradient ektacytometry-derived biomarkers are associated with vaso-occlusive crises and correlate with treatment response in sickle cell disease

Am J Hematol. 2021 Jan;96(1):E29-E32. doi: 10.1002/ajh.26031. Epub 2020 Nov 11.

Minke A E Rab^{1

2}, Celeste K Kanne³, Jennifer Bos¹, Brigitte A van Oirschot¹, Camille Boisson^{4

5}, Maite E Houwing⁶, Jorn Gerritsma⁷, Erik Teske⁸, Celine Renoux^{4

5

9}, Jurgen Riedl¹⁰, Roger E G Schutgens², Marije Bartels², Erfan Nur¹¹, Philippe Joly^{4

5

9}, Romain Fort¹², Marjon H Cnossen⁶, Richard van Wijk¹, Philippe Connes^{4

5}, Eduard J van Beers², Vivien A Sheehan³

¹ Central Diagnostic Laboratory-Research, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
² Van Creveldkliniek, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
³ Department of Pediatrics Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, Georgia, USA.
⁴ Laboratory LIBM EA7424, University of Lyon 1, "Vascular Biology and Red Blood Cell" team, Lyon, France.
⁵ Laboratory of Excellence GR-Ex, Paris, France.
⁶ Department of Pediatric Hematology, Erasmus Medical Center, Rotterdam, The Netherlands.
⁷ Emma Children's Hospital, Pediatric Hematology, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
⁸ Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
⁹ Laboratory of Biochemistry and Molecular Biology, UF Biochemistry of Red Blood Cell diseases, Est Center of Biology and Pathology, Hospices Civils de Lyon, Lyon, France.
¹⁰ Result Laboratory, Albert Schweitzer Hospital, Dordrecht, The Netherlands.
¹¹ Department of Hematology, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
¹² Department of Internal Medicine, Hospices Civils de Lyon, Lyon, France.

No abstract available

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