Smart materials in cardiovascular implants: Shape memory alloys and shape memory polymers

Artif Organs. 2021 May;45(5):454-463. doi: 10.1111/aor.13851. Epub 2020 Dec 9.

Abstract

Smart materials have intrinsic properties that change in a controlled fashion in response to external stimuli. Currently, the only smart materials with a significant clinical impact in cardiovascular implant design are shape memory alloys, particularly Nitinol. Recent prodigious progress in material science has resulted in the development of sophisticated shape memory polymers. In this article, we have reviewed the literature and outline the characteristics, advantages, and disadvantages of shape memory alloys and shape memory polymers which are relevant to clinical cardiovascular applications, and describe the potential of these smart materials for applications in coronary stents and transcatheter valves.

Keywords: biomaterials; cardiovascular implants; coronary stents; interventional cardiology; minimally invasive procedures; nitinol; shape memory alloys; shape memory polymers; smart materials; transcatheter valves.

Publication types

  • Review

MeSH terms

  • Cardiovascular Diseases / surgery*
  • Equipment Design
  • Humans
  • Materials Testing
  • Percutaneous Coronary Intervention / instrumentation*
  • Percutaneous Coronary Intervention / trends
  • Polymers / therapeutic use*
  • Smart Materials / therapeutic use*
  • Stents / trends
  • Transcatheter Aortic Valve Replacement / instrumentation*
  • Transcatheter Aortic Valve Replacement / trends

Substances

  • Polymers
  • Smart Materials