Successful salvage intravenous chemotherapy after tandem selective ophthalmic artery infusion chemotherapy in bilateral retinoblastoma

Hyun J Kim; Maura Di Nicola; James J Augsburger; Basil K Williams

doi:10.4103/ijo.IJO_576_20

Successful salvage intravenous chemotherapy after tandem selective ophthalmic artery infusion chemotherapy in bilateral retinoblastoma

Indian J Ophthalmol. 2020 Nov;68(11):2618-2620. doi: 10.4103/ijo.IJO_576_20.

Authors

Hyun J Kim¹, Maura Di Nicola¹, James J Augsburger¹, Basil K Williams¹

Affiliation

¹ Ocular Oncology Service, Department of Ophthalmology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

Abstract

We report the case of a 9-month-old girl with bilateral retinoblastoma who had incomplete tumor resolution after selective ophthalmic artery infusion chemotherapy (SOAIC). Systemic chemotherapy, rarely used as salvage therapy after SOAIC, with systemic carboplatin, etoposide, and vincristine achieved complete and sustained regression in both eyes.

Keywords: Intraarterial chemotherapy; retinoblastoma; selective ophthalmic artery infusion chemotherapy.

Publication types

Case Reports

MeSH terms

Antineoplastic Combined Chemotherapy Protocols
Carboplatin / therapeutic use
Female
Humans
Infant
Infusions, Intra-Arterial
Ophthalmic Artery
Retinal Neoplasms* / diagnosis
Retinal Neoplasms* / drug therapy
Retinoblastoma* / diagnosis
Retinoblastoma* / drug therapy
Retrospective Studies
Salvage Therapy

Substances

Carboplatin