Rationale: With the development of endoscopic techniques, endoscopic therapy began to play an important role in the management of esophageal hemangiomas.
Patients concerns: A large esophageal submucosal tumor (2.5 cm), which was suspected to be an esophageal hemangioma, was diagnosed in a 50-year-old woman.
Diagnosis: Esophageal hemangioma INTERVENTIONS:: Endoscopic submucosal dissection was performed for tumor removal.
Outcomes: Histopathological results revealed hemangioma. No complication or recurrence was observed in the 17-month follow-up period.
Lessons: Our successful experience showed that endoscopic submucosal dissection is an effective and a safe approach to treat large esophageal hemangiomas (2.5 cm).