Antimicrobial Stewardship: What the Clinical Laboratory Needs to Know

Clin Lab Med. 2020 Dec;40(4):509-520. doi: 10.1016/j.cll.2020.08.008. Epub 2020 Oct 6.

Abstract

Misuse of antibiotics, including unnecessary use or inappropriate selection, may result in side effects and poor outcome in individual patients, as well as contribute to the spread of antimicrobial resistance. Antimicrobial stewardship programs exist to reduce such misuse of antibiotics and ill effect in order to promote patient outcome. The importance of diagnostics, antibiogram data, possible interventions, and impact are reviewed. It is essential for clinical microbiologists and other health care members to understand the field and scope of antimicrobial stewardship, actively participate in, and understand the value they bring to supporting their institution's efforts.

Keywords: Antibiogram; Antimicrobial misuse; Antimicrobial resistance; Antimicrobial stewardship programs; Handshake stewardship; Prior authorization; Prospective audit; Rapid diagnostics.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / adverse effects
  • Anti-Bacterial Agents / pharmacology
  • Anti-Bacterial Agents / therapeutic use
  • Antimicrobial Stewardship*
  • Drug Resistance, Microbial
  • Humans
  • Inappropriate Prescribing / prevention & control
  • Laboratories*
  • Microbial Sensitivity Tests
  • Prior Authorization

Substances

  • Anti-Bacterial Agents