Expanding donor pool by utilizing deceased donors with snake envenoming

Clin Transplant. 2020 Dec;34(12):e14135. doi: 10.1111/ctr.14135. Epub 2020 Nov 20.

Abstract

In India, the deceased kidney transplant program is still in its preliminary stage, and accepting deceased donors with snakebite is just a forward step to expand the donor pool. We report here the outcome of 8 successful renal transplantations from brain-dead donors who died from a neurotoxic snakebite. We accepted them as donors as they had no evidence of hemotoxic snakebite. 7 recipients did well. 1 died due to sepsis with a functioning graft. 1 required renal biopsy that showed acute tubular necrosis. 1 required re-exploration due to graft collection due to a surgical issue. Patient and graft survival in follow-up were similar to other matched deceased donors in our center. According to our experience, utilizing brain-dead donors who died from a neurotoxic snakebite is safe and may dramatically expand the donor pool especially in countries where death due to snakebite is high in numbers.

Keywords: deceased donor; developing nation; organ wastage; snakebite.

MeSH terms

  • Antivenins
  • Graft Survival
  • Humans
  • India
  • Snake Bites*
  • Snake Venoms
  • Tissue Donors
  • Treatment Outcome

Substances

  • Antivenins
  • Snake Venoms