Same-day prescribing of daily oral pre-exposure prophylaxis for HIV prevention

Lancet HIV. 2021 Feb;8(2):e114-e120. doi: 10.1016/S2352-3018(20)30256-3. Epub 2020 Oct 28.

Abstract

Pre-exposure prophylaxis (PrEP) is highly effective in reducing HIV transmission but remains underutilised globally. Same-day PrEP prescribing and medication provision is an emerging implementation approach. The experiences of the three same-day PrEP programmes support the feasibility of the approach. Key elements of safe and effective same-day PrEP programmes include the ability to order laboratory tests at the time of the clinical visit and the ability to contact patients when laboratory results are available. Same-day PrEP has the potential to alleviate the attrition seen in usual care between initial evaluation and receipt of a PrEP prescription. A widespread application of same-day prescribing will be needed to assess its effect on PrEP usage.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Administration, Oral
  • Adolescent
  • Adult
  • Anti-HIV Agents / administration & dosage*
  • Drug Prescriptions
  • Emtricitabine / administration & dosage*
  • Female
  • HIV / drug effects
  • HIV Infections / epidemiology*
  • HIV Infections / prevention & control*
  • Humans
  • Male
  • Practice Patterns, Physicians'
  • Pre-Exposure Prophylaxis / methods*
  • Safe Sex
  • Tenofovir / administration & dosage*
  • United States / epidemiology

Substances

  • Anti-HIV Agents
  • Tenofovir
  • Emtricitabine