Sca1⁺ Cells Minimally Contribute to Smooth Muscle Cells in Atherosclerosis

Circ Res. 2021 Jan 8;128(1):133-135. doi: 10.1161/CIRCRESAHA.120.317972. Epub 2020 Nov 4.

Authors

Haixiao Wang^#¹, Huan Zhao^#¹, Huan Zhu^#¹, Yi Li¹, Juan Tang¹, Yan Li¹, Bin Zhou^{1

2

3}

Affiliations

¹ State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences (H.W., H. Zhao, H. Zhu, Yi Li, J.T., Yan Li, B.Z.), University of Chinese Academy of Sciences, Shanghai.
² School of Life Science, Hangzhou Institute for Advanced Study (B.Z.), University of Chinese Academy of Sciences, Shanghai.
³ School of Life Science and Technology, ShanghaiTech University, University of Chinese Academy of Sciences, Hangzhou, China (B.Z.).

^# Contributed equally.

PMID: 33146591
DOI: 10.1161/CIRCRESAHA.120.317972

No abstract available

Keywords: actin; atherosclerosis; calponin; cell lineage; neointima.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Antigens, Ly / genetics
Antigens, Ly / metabolism*
Aorta / metabolism
Aorta / pathology
Atherosclerosis / genetics
Atherosclerosis / metabolism*
Atherosclerosis / pathology
Cell Lineage*
Cell Plasticity*
Cell Proliferation
Disease Models, Animal
Female
Male
Membrane Proteins / genetics
Membrane Proteins / metabolism*
Mice
Mice, Inbred C57BL
Mice, Knockout
Muscle, Smooth, Vascular / metabolism*
Muscle, Smooth, Vascular / pathology
Myocytes, Smooth Muscle / metabolism*
Myocytes, Smooth Muscle / pathology
Neointima
Phenotype
Plaque, Atherosclerotic
Receptors, LDL / genetics
Receptors, LDL / metabolism

Substances

Antigens, Ly
Ly6a protein, mouse
Membrane Proteins
Receptors, LDL