Challenges and opportunities at the interface of birth defects, human genetics and developmental biology

Mustafa K Khokha; Karen J Liu; John B Wallingford

doi:10.1242/dev.197871

Challenges and opportunities at the interface of birth defects, human genetics and developmental biology

Development. 2020 Nov 9;147(21):dev197871. doi: 10.1242/dev.197871.

Authors

Mustafa K Khokha¹, Karen J Liu², John B Wallingford³

Affiliations

¹ Pediatric Genomics Discovery Program, Department of Pediatrics and Genetics, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA [email protected].
² Centre for Craniofacial and Regenerative Biology, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London SE1 9RT, UK.
³ Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA.

Abstract

Summary: This Spotlight summarizes conclusions from The Company of Biologists Workshop ‘Understanding Human Birth Defects in the Genomic Age’ held in the UK in November 2019, identifying key hurdles in the field, as well as priorities for overcoming them.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review

MeSH terms

Congenital Abnormalities / genetics*
Congenital Abnormalities / mortality
Cooperative Behavior
Developmental Biology*
Genetic Variation
Genotype
Human Genetics*
Humans
Infant
Phenotype

Abstract

Publication types

MeSH terms

Grants and funding