[Drug approval : entrectinib and larotrectinib - cancers with NTRK fusion]

Bull Cancer. 2020 Nov;107(11):1085-1086. doi: 10.1016/j.bulcan.2020.09.009. Epub 2020 Oct 21.
[Article in French]
No abstract available

Publication types

  • Letter
  • News

MeSH terms

  • Adult
  • Benzamides / adverse effects
  • Benzamides / therapeutic use*
  • Child
  • Drug Approval*
  • France
  • Humans
  • Indazoles / adverse effects
  • Indazoles / therapeutic use*
  • Membrane Glycoproteins / genetics
  • Neoplasms / drug therapy*
  • Neoplasms / genetics
  • Neoplasms / mortality
  • Oncogene Proteins, Fusion*
  • Protein Kinase Inhibitors / adverse effects
  • Protein Kinase Inhibitors / therapeutic use*
  • Pyrazoles / adverse effects
  • Pyrazoles / therapeutic use*
  • Pyrimidines / adverse effects
  • Pyrimidines / therapeutic use*
  • Receptor, trkA / genetics
  • Receptor, trkB / genetics
  • Receptor, trkC / genetics

Substances

  • Benzamides
  • Indazoles
  • Membrane Glycoproteins
  • NTRK1 protein, human
  • NTRK3 protein, human
  • Oncogene Proteins, Fusion
  • Protein Kinase Inhibitors
  • Pyrazoles
  • Pyrimidines
  • Receptor, trkA
  • Receptor, trkB
  • Receptor, trkC
  • tropomyosin-related kinase-B, human
  • entrectinib
  • larotrectinib