BCG in management of superficial bladder cancer

Urology. 1987 Dec;30(6):515-9. doi: 10.1016/0090-4295(87)90428-6.

Abstract

Superficial bladder cancer and particularly carcinoma in situ has the potential for invasiveness for which the treatment is cystectomy with a resultant disappointing 50 per cent five-year survival and urinary diversion with a certain diminished quality of life. BCG therapy is a new method of treating aggressive superficial bladder cancer with better response rates than conventional chemotherapy. It may be immunologically mediated and, if so, may be the first major success of a therapeutic modality that offers less morbidity than the currently standard options of surgery, radiotherapy, or chemotherapy.

Publication types

  • Clinical Trial
  • Comparative Study
  • Review

MeSH terms

  • Administration, Intravesical
  • Algorithms
  • BCG Vaccine / therapeutic use*
  • Carcinoma in Situ / therapy*
  • Carcinoma, Transitional Cell / therapy*
  • Clinical Trials as Topic
  • Humans
  • Urinary Bladder Neoplasms / therapy*

Substances

  • BCG Vaccine