Cerebral Infarction With Increased Uptake on 123I-FP-CIT SPECT

Satoshi Nakajima; Yasutaka Fushimi; Hirotsugu Kawashima; Toshiya Murai; Yuji Nakamoto

doi:10.1097/RLU.0000000000003366

Cerebral Infarction With Increased Uptake on 123I-FP-CIT SPECT

Clin Nucl Med. 2021 Apr 1;46(4):e193-e194. doi: 10.1097/RLU.0000000000003366.

Authors

Satoshi Nakajima¹, Yasutaka Fushimi¹, Hirotsugu Kawashima², Toshiya Murai², Yuji Nakamoto¹

Affiliations

¹ From the Departments of Diagnostic Imaging and Nuclear Medicine.
² Psychiatry, Kyoto University Graduate School of Medicine, Kyoto, Japan.

PMID: 33181738
DOI: 10.1097/RLU.0000000000003366

Abstract

A 76-year-old woman underwent 123I-FP-CIT brain SPECT due to postural reflex impairment. The transverse slices demonstrated increased uptake in the right middle cerebral artery territory. MR images obtained 2 weeks earlier showed cerebral infarction in the corresponding area. 123I-FP-CIT has high binding affinity for dopamine transporters, especially in the nerve endings of nigrostriatal dopaminergic neurons.

Publication types

Case Reports

MeSH terms

Aged
Biological Transport
Cerebral Infarction / diagnostic imaging*
Cerebral Infarction / metabolism*
Dopamine Plasma Membrane Transport Proteins / metabolism
Female
Humans
Tomography, Emission-Computed, Single-Photon*
Tropanes / metabolism*

Substances

Dopamine Plasma Membrane Transport Proteins
Tropanes
2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropane