Paraneoplastic limbic encephalitis (PLE) is a rare disease with established diagnostic criteria. We describe a case of an uncommon presentation of PLE in a female who presented with a one- year duration of short-term memory loss and mild behavioral changes who was eventually diagnosed with PLE associated with breast cancer. Our case demonstrates atypical presentation of PLE, with chronic presentation and an uncharacteristic mild neurological symptoms. This case aims to highlight the importance of a diagnostic work up of autoimmune encephalitis in selected cases that does not present with common diagnostic criteria.
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