Effect of mesoporous silica nanoparticles-based nano-fragrance on the central nervous system

Zhiguo Lu; Tianlu Zhang; Jun Yang; Jianze Wang; Jie Shen; Xiangyu Wang; Zuobing Xiao; Yunwei Niu; Guiying Liu; Xin Zhang

doi:10.1002/elsc.202000015

Effect of mesoporous silica nanoparticles-based nano-fragrance on the central nervous system

Eng Life Sci. 2020 Jun 4;20(11):535-540. doi: 10.1002/elsc.202000015. eCollection 2020 Nov.

Authors

Zhiguo Lu^{1

2}, Tianlu Zhang^{1

2}, Jun Yang¹, Jianze Wang¹, Jie Shen^{1

2}, Xiangyu Wang¹, Zuobing Xiao^{3

4}, Yunwei Niu^{3

4}, Guiying Liu⁵, Xin Zhang¹

Affiliations

¹ State Key Laboratory of Biochemical Engineering, Institute of Process Engineering Chinese Academy of Sciences Beijing P. R. China.
² University of Chinese Academy of Sciences Beijing P. R. China.
³ Shanghai Research Institute of Fragrance and Flavor Industry Shanghai P. R. China.
⁴ School of Perfume and Aroma Technology Shanghai Institute of Technology Shanghai P. R. China.
⁵ Department of Pediatrics Capital Medical University Affiliated Beijing Anzhen Hospital Beijing P. R. China.

Abstract

Fragrances are widely used in our daily lives and can make us feel happy. However, traditional aromatic products release fragrance quickly and have a strong aroma. This not only worsens our scenting experience, but also severely shortens the useful life of fragrance products. In this study, nano-fragrances based on mesoporous silica nanoparticles with great encapsulation efficiency and slow-release function were designed and prepared. In addition, this nano-fragrances are applied to wallpapers. Open field tests showed that this nano-fragrance had significant stress relief and anti-depressant effects.

Keywords: central nervous system; encapsulation efficiency; fragrance; silica nanoparticles; wallpaper.