Perineal desquamation: An early sign of the Kawasaki disease phenotype of MIS-C

Daniel R Mazori; Kristina M Derrick; Urvi Kapoor; Minoti Haribhai; Ramon E Gist; Sharon A Glick

doi:10.1111/pde.14462

Perineal desquamation: An early sign of the Kawasaki disease phenotype of MIS-C

Pediatr Dermatol. 2021 Jan;38(1):253-256. doi: 10.1111/pde.14462. Epub 2020 Nov 22.

Authors

Daniel R Mazori¹, Kristina M Derrick¹, Urvi Kapoor², Minoti Haribhai², Ramon E Gist³, Sharon A Glick¹

Affiliations

¹ Department of Dermatology, SUNY Downstate Health Sciences University, Brooklyn, NY, USA.
² Department of Pediatrics, SUNY Downstate Health Sciences University, Brooklyn, NY, USA.
³ Division of Critical Care, Department of Pediatrics, SUNY Downstate Health Sciences University, Brooklyn, NY, USA.

PMID: 33222290
DOI: 10.1111/pde.14462

Abstract

Multisystem inflammatory syndrome in children (MIS-C) is a syndrome associated with coronavirus disease 2019. Various phenotypes of MIS-C have been described including Kawasaki disease (KD). Although perineal desquamation is a known early sign of KD, to our knowledge, this rash has not yet been described in the KD phenotype of MIS-C. In this article, we report two patients in whom perineal desquamation was an early clue for the KD phenotype of MIS-C.

Keywords: COVID-19; Kawasaki disease; MIS-C; Multisystem Inflammatory Syndrome in Children; coronavirus disease 2019; perineal desquamation; skin of color.

Publication types

Case Reports

MeSH terms

COVID-19 / diagnosis*
Child, Preschool
Diagnosis, Differential
Humans
Infant
Male
Mucocutaneous Lymph Node Syndrome / diagnosis*
Perineum / pathology*
Phenotype
Skin Diseases, Infectious / pathology*
Systemic Inflammatory Response Syndrome / diagnosis*

Supplementary concepts

pediatric multisystem inflammatory disease, COVID-19 related