Non-IgE adverse reactions to biologics

J Allergy Clin Immunol. 2021 Apr;147(4):1204-1206. doi: 10.1016/j.jaci.2020.11.012. Epub 2020 Nov 20.

Authors

Leticia de Las Vecillas¹, Mariana Castells²

Affiliations

¹ Department of Allergy, Marqués de Valdecilla University Hospital-Instituto de Investigación Marqués de Valdecilla (IDIVAL), Santander, Spain.
² Division of Allergy and Clinical Immunology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass. Electronic address: [email protected].

PMID: 33227316
DOI: 10.1016/j.jaci.2020.11.012

No abstract available

Keywords: Biologics; adverse reactions; antidrug antibodies; biomarkers; desensitization; endotype; non–IgE-mediated reactions; phenotype.

Publication types

Editorial
Review

MeSH terms

Animals
Biological Products / adverse effects*
Biomarkers / blood
Desensitization, Immunologic / methods*
Drug Hypersensitivity / immunology*
Drug-Related Side Effects and Adverse Reactions / immunology*
Humans
Immunoglobulin E / metabolism
Interleukin-6 / blood
Tryptases / blood

Substances

Biological Products
Biomarkers
Interleukin-6
Immunoglobulin E
Tryptases