Carbapenem-resistant Klebsiella pneumoniae in ICU-admitted COVID-19 patients: Keep an eye on the ball

G Montrucchio; S Corcione; G Sales; A Curtoni; F G De Rosa; L Brazzi

doi:10.1016/j.jgar.2020.11.004

Carbapenem-resistant Klebsiella pneumoniae in ICU-admitted COVID-19 patients: Keep an eye on the ball

J Glob Antimicrob Resist. 2020 Dec:23:398-400. doi: 10.1016/j.jgar.2020.11.004. Epub 2020 Nov 23.

Authors

G Montrucchio¹, S Corcione², G Sales³, A Curtoni⁴, F G De Rosa⁵, L Brazzi⁶

Affiliations

¹ Anestesia e Rianimaizone 1U, Department of Anesthesia, Intensive Care and Emergency, 'Città della Salute e della Scienza' Hospital, Turin, Italy; Department of Surgical Sciences, University of Turin, Turin, Italy. Electronic address: [email protected].
² Department of Medical Sciences, Infectious Diseases, University of Turin, Turin, Italy; Tufts School of Medicine, Boston, MA, USA.
³ Anestesia e Rianimaizone 1U, Department of Anesthesia, Intensive Care and Emergency, 'Città della Salute e della Scienza' Hospital, Turin, Italy.
⁴ Microbiology and Virology Unit, 'Città Della Salute e Della Scienza' Hospital, Turin, Italy.
⁵ Department of Medical Sciences, Infectious Diseases, University of Turin, Turin, Italy.
⁶ Anestesia e Rianimaizone 1U, Department of Anesthesia, Intensive Care and Emergency, 'Città della Salute e della Scienza' Hospital, Turin, Italy; Department of Surgical Sciences, University of Turin, Turin, Italy.

Abstract

Here we report on seven intensive care unit (ICU) patients with coronavirus disease 2019 (COVID-19)-related acute respiratory distress syndrome (ARDS) who developed positive rectal swabs and invasive infections due to carbapenemase-producing Klebsiella pneumoniae (CP-Kp). Notwithstanding the infection prevention measures introduced during the COVID-19 pandemic and changes in the hospitalised population, attention to CP-Kp infections must remain high, especially in the critically ill setting.

Keywords: Antimicrobial resistance; COVID-19; Carbapenem-resistant Klebsiella pneumonia; Carbapenemase; Infection control; Superinfection.

MeSH terms

Adult
Aged
COVID-19 / diagnosis
COVID-19 / epidemiology
COVID-19 / microbiology*
COVID-19 / therapy
Carbapenem-Resistant Enterobacteriaceae / isolation & purification*
Coinfection / epidemiology
Critical Illness
Female
Humans
Intensive Care Units / statistics & numerical data
Italy / epidemiology
Klebsiella Infections / epidemiology
Klebsiella Infections / microbiology
Klebsiella Infections / therapy
Klebsiella Infections / virology*
Klebsiella pneumoniae / isolation & purification*
Male
Middle Aged
SARS-CoV-2 / isolation & purification