Upper Gastrointestinal Cancer Management in the COVID-19 Era: Risk of Infection, Adapted Role of Endoscopy, and Potential Treatment Algorithm Alterations

J Gastrointest Cancer. 2021 Jun;52(2):407-413. doi: 10.1007/s12029-020-00557-y. Epub 2020 Nov 26.

Abstract

Introduction: The safety of upper gastrointestinal cancer patients in the SARS-CoV-2 outbreak is extremely important and most surgeons need to establish a contingency management.

Aim: In this study, we present the surgical outlines of patients suffering from upper gastrointestinal cancers.

Materials and methods: Data were obtained from PubMed, Cochrane Database of Controlled Trials, and SCOPUS of reports up to September 2020.

Results: The COVID-19 outbreak makes surgical procedures extremely difficult to be performed. The most common criteria to prioritize patients for surgical treatment are stage, tumor biology, presence of tumor-related symptoms, the risk of tumor to become non-resectable, and time interval from neoadjuvant therapy. The multidisciplinary teams can help assigning a priority level to each clinical case.

Conclusion: We have to continue providing treatment to oncologic patients in the face of COVID-19 uncertainty, with higher caution and responsibility in order to develop a safer and more effective personalized treatment plan.

Keywords: COVID-19; Pandemic; Surgery; Upper gastrointestinal cancers.

Publication types

  • Review

MeSH terms

  • Algorithms
  • COVID-19 / epidemiology*
  • COVID-19 / etiology
  • Endoscopy, Gastrointestinal*
  • Gastrointestinal Neoplasms / complications
  • Gastrointestinal Neoplasms / diagnosis
  • Gastrointestinal Neoplasms / surgery*
  • Humans
  • Risk Factors
  • SARS-CoV-2*
  • Upper Gastrointestinal Tract