Daunomycin- and adriamycin-N-(2-hydroxypropyl)methacrylamide copolymer conjugates; toxicity reduction by improved drug-delivery

Cancer Treat Rev. 1987 Dec;14(3-4):319-27. doi: 10.1016/0305-7372(87)90024-7.

Authors

L W Seymour¹, R Duncan, P Kopecková, J Kopecek

Affiliation

¹ Department of Biological Sciences, University of Keele, Staffordshire, U.K.

PMID: 3326668
DOI: 10.1016/0305-7372(87)90024-7

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Antineoplastic Agents / therapeutic use
Antineoplastic Agents / toxicity*
Chemical Phenomena
Chemistry
Daunorubicin / therapeutic use
Daunorubicin / toxicity*
Doxorubicin / analogs & derivatives*
Doxorubicin / therapeutic use
Doxorubicin / toxicity
Drug Carriers
Leukemia L1210 / drug therapy
Mice
Polymethacrylic Acids / therapeutic use
Polymethacrylic Acids / toxicity*

Substances

Antineoplastic Agents
Drug Carriers
Polymethacrylic Acids
daunomycin-N-(2-hydroxypropyl)methacrylamide copolymer conjugate
doxorubicin-N-(2-hydroxypropyl)methacrylamide copolymer conjugate
Doxorubicin
Daunorubicin