A case of severe course of COVID-19 treated with experimental therapy

Cas Lek Cesk. 2020 Summer;159(5):181-184.

Abstract

70-year-old high-risk patient with severe course of COVID-19 hospitalized for progressive dyspnea due to extensive bilateral pneumonia caused by SARS-CoV-2. The patient was treated with hydroxychloroquine and azithromycin from day one of hospital stay. Because of progression on the therapy, the convalescent plasma was administered on day three of hospitalization. The patient subsequently improved and was discharged home on day eleven of the hospital stay. Risk factors of severe course of the infection, complications and potential therapies of COVID-19 are discussed.

Keywords: COVID-19; SARS-CoV-2; azithromycin; blood plasma; hydroxychloroquine; viral pneumonia.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antiviral Agents* / therapeutic use
  • Azithromycin / therapeutic use
  • COVID-19 Serotherapy
  • COVID-19* / therapy
  • Humans
  • Hydroxychloroquine / therapeutic use
  • Immunization, Passive
  • Pandemics
  • SARS-CoV-2
  • Therapies, Investigational

Substances

  • Antiviral Agents
  • Hydroxychloroquine
  • Azithromycin