Anti-neoplastic drugs have made major advancements in oncology, however they are not without cardiovascular consequences. We present a patient with cutaneous T-cell lymphoma receiving Targretin therapy who presented with accelerated atherosclerosis. His triglyceride level (TG) was greater than 1000 mg/dL, which rapidly improved with discontinuation of Targretin.
Keywords: Atherosclerosis; Atypical angina; Cutaneous T-cell lymphoma; Primary hypertriglyceridemia; Targretin (Bexarotene).