A randomised pilot trial of combined cognitive and physical exercise prehabilitation to improve outcomes in surgical patients

Kimberly F Rengel; Nitin Mehdiratta; Susan W Vanston; Kristin R Archer; James C Jackson; Jennifer L Thompson; Pratik P Pandharipande; Christopher G Hughes

doi:10.1016/j.bja.2020.11.004

A randomised pilot trial of combined cognitive and physical exercise prehabilitation to improve outcomes in surgical patients

Br J Anaesth. 2021 Feb;126(2):e55-e57. doi: 10.1016/j.bja.2020.11.004. Epub 2020 Dec 13.

Authors

Kimberly F Rengel¹, Nitin Mehdiratta², Susan W Vanston³, Kristin R Archer⁴, James C Jackson⁵, Jennifer L Thompson⁶, Pratik P Pandharipande⁷, Christopher G Hughes⁷

Affiliations

¹ Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Anesthesiology, Division of Anesthesia Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address: [email protected].
² Department of Anesthesiology, Division of Anesthesia Critical Care and GVT, Duke University School of Medicine, Durham, NC, USA.
³ Department of Orthopedic Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
⁴ Department of Orthopedic Surgery, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Physical Medicine and Rehabilitation, Vanderbilt University Medical Center, Nashville, TN, USA.
⁵ Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center, Vanderbilt University Medical Center, Nashville, TN, USA; The Center for Health Services Research, Vanderbilt University Medical Center, Nashville, TN, USA; Geriatric Research, Education and Clinical Center (GRECC) Service, Nashville Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN, USA; Department of Psychiatry, Vanderbilt University Medical Center, Nashville, TN, USA.
⁶ Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN, USA.
⁷ Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Anesthesiology, Division of Anesthesia Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, USA; Nashville Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN, USA.

No abstract available

Keywords: acquired disability; major surgery; postoperative neurocognitive disorder; prehabilitation; quality of life.

Publication types

Letter
Randomized Controlled Trial
Research Support, N.I.H., Extramural

MeSH terms

Aged
Cognition
Cognitive Behavioral Therapy*
Feasibility Studies
Female
Functional Status*
Humans
Male
Middle Aged
Pilot Projects
Postoperative Cognitive Complications / etiology
Postoperative Cognitive Complications / prevention & control*
Postoperative Cognitive Complications / psychology
Preoperative Exercise*
Recovery of Function
Resistance Training*
Tennessee
Time Factors
Treatment Outcome

Grants and funding

UL1 TR002243/TR/NCATS NIH HHS/United States