Pre-Existing Cytokine and NLRP3 Inflammasome Activation and Increased Vascular Permeability in Diabetes: A Possible Fatal Link With Worst COVID-19 Infection Outcomes?

Front Immunol. 2020 Nov 23:11:557235. doi: 10.3389/fimmu.2020.557235. eCollection 2020.
No abstract available

Keywords: cytokine; diabetes; glycocalyx; inflammasome; inflammation.

Publication types

  • Review

MeSH terms

  • Adult
  • Aged
  • COVID-19* / complications
  • COVID-19* / immunology
  • COVID-19* / mortality
  • Capillary Permeability / immunology*
  • Cytokines / immunology*
  • Diabetes Complications* / etiology
  • Diabetes Complications* / immunology
  • Diabetes Complications* / mortality
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pandemics*
  • Risk Factors
  • SARS-CoV-2 / immunology*

Substances

  • Cytokines