Gynecologic Care for Pediatric and Adolescent Patients Undergoing Hematopoietic Stem Cell Transplantation

J Pediatr Adolesc Gynecol. 2021 Apr;34(2):112-116. doi: 10.1016/j.jpag.2020.12.007. Epub 2020 Dec 16.

Abstract

Hematopoietic stem cell transplantation is used to treat many chronic and acute malignant and nonmalignant conditions. We review hematopoietic stem cell transplantation and its effect on the gynecologic health of pediatric and adolescent patients, including pretransplantation evaluation, contraception, menstrual suppression, sexual health, fertility, primary ovarian insufficiency, and graft vs host disease. Comprehensive and team-based care provides optimal anticipatory counseling, evaluation, and management of acute and ongoing gynecologic issues.

Keywords: Graft versus host disease; Oncology; hematopoietic stem cell transplant.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Child
  • Female
  • Genital Diseases, Female / prevention & control*
  • Graft vs Host Disease / prevention & control*
  • Hematopoietic Stem Cell Transplantation*
  • Humans
  • Perioperative Care / methods
  • Preoperative Care / methods
  • Reproductive Health*
  • Sexual Health*