Late reactivation of cherubism in an adult further to local inflammation

J Stomatol Oral Maxillofac Surg. 2022 Feb;123(1):85-87. doi: 10.1016/j.jormas.2020.12.005. Epub 2020 Dec 18.

Abstract

Cherubism is a rare pediatric disease affecting the jaw. It appears among children between 2 and 5 years old. Maximum growth is observed at 7-8 years old, then lesions remain unchanged or increase slowly until puberty. Only 2 cases of later growth have been reported. We describe a case of cherubism reactivation in a 46-year-old woman. Appearance of a new lesion occurs in a context of local inflammation due to repeated friction of the dental prosthesis on the mandible. No article in the literature describes a similar case. This case shows the determining role of inflammation (local or general) in the pathophysiology of cherubism.

Keywords: Adult; Cherubism; Local inflammation; Reactivation.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cherubism* / diagnosis
  • Cherubism* / pathology
  • Child
  • Child, Preschool
  • Female
  • Head
  • Humans
  • Inflammation / diagnosis
  • Inflammation / pathology
  • Mandible / pathology
  • Middle Aged