Antibody Responses 8 Months after Asymptomatic or Mild SARS-CoV-2 Infection

Emerg Infect Dis. 2021 Mar;27(3):928-931. doi: 10.3201/eid2703.204543. Epub 2020 Dec 22.

Abstract

Waning humoral immunity in coronavirus disease patients has raised concern over usefulness of serologic testing. We investigated antibody responses of 58 persons 8 months after asymptomatic or mildly symptomatic infection with severe acute respiratory syndrome coronavirus 2. For 3 of 4 immunoassays used, seropositivity rates were high (69.0%-91.4%).

Keywords: 2019 novel coronavirus disease; COVID-19; ECLIA; ELISA; SARS-CoV-2; antibody; coronavirus disease; respiratory infections; severe acute respiratory syndrome coronavirus 2; viruses; zoonoses.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antibodies, Viral / blood*
  • Asymptomatic Infections
  • COVID-19 / epidemiology
  • COVID-19 / immunology*
  • Cross-Sectional Studies
  • Female
  • Humans
  • Immunity, Humoral*
  • Male
  • Republic of Korea
  • SARS-CoV-2 / immunology
  • Young Adult

Substances

  • Antibodies, Viral