Chronic lymphocytic leukemia increases the pool of peripheral blood hematopoietic stem cells and skews differentiation

Blood Adv. 2020 Dec 22;4(24):6310-6314. doi: 10.1182/bloodadvances.2020002863.

Abstract

  1. CLL increases the pool of ST-HSCs in the peripheral blood.

  2. Differentiation of CLL-derived peripheral blood HSPCs is skewed toward the myeloid lineage.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Differentiation
  • Hematopoietic Stem Cell Transplantation*
  • Hematopoietic Stem Cells
  • Humans
  • Leukemia, Lymphocytic, Chronic, B-Cell*