Cell Biology: Pardon the Intrusion

Scott E Williams; Kendall J Lough

doi:10.1016/j.cub.2020.10.036

Cell Biology: Pardon the Intrusion

Curr Biol. 2020 Dec 21;30(24):R1481-R1484. doi: 10.1016/j.cub.2020.10.036.

Authors

Scott E Williams¹, Kendall J Lough²

Affiliations

¹ Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC 27599, USA. Electronic address: [email protected].
² Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA.

PMID: 33352130
DOI: 10.1016/j.cub.2020.10.036

Abstract

Whilst tissues form during development, some cells are extruded from epithelial monolayers. Rather than dying or differentiating, a new study shows that displaced cells can reintegrate after dividing. Surprisingly, this 'intrusion' pathway shares common features with axon guidance.

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MeSH terms

Axon Guidance*
Axons*
Epithelium