Increasing intraoperative hydromorphone does not decrease postoperative pain: a retrospective observational study

Br J Anaesth. 2021 Mar;126(3):e95-e97. doi: 10.1016/j.bja.2020.11.026. Epub 2021 Jan 6.
No abstract available

Keywords: acute hyperalgesia; acute tolerance; hip surgery; hydromorphone; knee surgery; opioid-induced hyperalgesia; orthopaedic surgery; postoperative pain.

Publication types

  • Letter
  • Research Support, N.I.H., Extramural

MeSH terms

  • Analgesics, Opioid / administration & dosage*
  • Anesthesia, General
  • Arthroplasty, Replacement, Hip
  • Arthroplasty, Replacement, Knee
  • Drug Administration Schedule
  • Female
  • Humans
  • Hydromorphone / administration & dosage*
  • Hyperalgesia / chemically induced
  • Intraoperative Care / methods*
  • Male
  • Observational Studies as Topic
  • Pain Management / methods*
  • Pain, Postoperative / drug therapy*
  • Retrospective Studies

Substances

  • Analgesics, Opioid
  • Hydromorphone