Variation in the availability and cost of essential medicines for non-communicable diseases in Uganda: A descriptive time series analysis

PLoS One. 2020 Dec 23;15(12):e0241555. doi: 10.1371/journal.pone.0241555. eCollection 2020.

Abstract

Background: Availability of essential medicines for non-communicable diseases (NCDs) is poor in low- and middle-income countries. Availability and cost are conventionally assessed using cross-sectional data. However, these characteristics may vary over time.

Methods: We carried out a prospective, descriptive analysis of the availability and cost of essential medicines in 23 Ugandan health facilities over a five-week period. We surveyed facility pharmacies in-person up to five times, recording availability and cost of 19 essential medicines for NCDs and four essential medicines for communicable diseases.

Results: Availability of medicines varied substantially over time, especially among public facilities. Among private-for-profit facilities, the cost of the same medicine varied from week to week. Private-not-for-profit facilities experienced less dramatic fluctuations in price.

Conclusions: We conclude that there is a need for standardized, continuous monitoring to better characterize the availability and cost of essential medicines, understand demand for these medicines, and reduce uncertainty for patients.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Communicable Diseases / drug therapy
  • Communicable Diseases / economics
  • Drug Costs* / trends
  • Drugs, Essential / economics*
  • Drugs, Essential / supply & distribution*
  • Health Facilities / economics
  • Health Services Accessibility / economics
  • Health Services Accessibility / trends
  • Humans
  • Noncommunicable Diseases / drug therapy*
  • Noncommunicable Diseases / economics
  • Private Sector / economics
  • Prospective Studies
  • Public Sector / economics
  • Surveys and Questionnaires
  • Time Factors
  • Uganda

Substances

  • Drugs, Essential

Grants and funding

The MacMillan Center of Yale University and the Yale Global Health Leadership Institute provided funding to support travel for JIS through the Hecht-Albert Pilot Innovation Award for Junior Faculty. Knoema provided funding for data collection and the development of the data collection and management tool. The funders played no further role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript.