Germline and somatic genetic alterations in two first-degree relatives with appendiceal low-grade mucinous carcinoma peritonei

Clin Case Rep. 2020 Sep 29;8(12):3168-3177. doi: 10.1002/ccr3.3338. eCollection 2020 Dec.

Abstract

Comparing genetic mutations of first-degree relatives with appendiceal pseudomyxoma peritonei may explain clinical outcomes and disease pathogenesis. Molecular profiling of mucinous tumors may identify improved treatments to traditional chemotherapy.

Keywords: appendix cancer; genetic analysis; hyperthermic intraperitoneal chemotherapy; next‐generation sequencing; pseudomyxoma peritonei.

Publication types

  • Case Reports