Prosopagnosia seizure semiology in a 10-year-old boy: a functional neuroimaging study

BMJ Case Rep. 2020 Dec 22;13(12):e237228. doi: 10.1136/bcr-2020-237228.

Abstract

We illustrate a case of post-traumatic recurrent transient prosopagnosia in a paediatric patient with a right posterior inferior temporal gyrus haemorrhage seen on imaging and interictal electroencephalogram abnormalities in the right posterior quadrant. Face recognition area mapping with magnetoencephalography (MEG) and functional MRI (fMRI) was performed to clarify the relationship between the lesion and his prosopagnosia, which showed activation of the right fusiform gyrus that colocalised with the lesion. Lesions adjacent to the right fusiform gyrus can result in seizures presenting as transient prosopagnosia. MEG and fMRI can help to attribute this unique semiology to the lesion.

Keywords: epilepsy and seizures; neuroimaging; neurosurgery; paediatric surgery.

Publication types

  • Case Reports

MeSH terms

  • Brain Mapping
  • Cerebral Hemorrhage / complications
  • Cerebral Hemorrhage / diagnosis*
  • Cerebral Hemorrhage / surgery
  • Child
  • Electroencephalography
  • Facial Recognition / physiology
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Neurosurgical Procedures*
  • Prosopagnosia / diagnosis
  • Prosopagnosia / etiology*
  • Prosopagnosia / physiopathology
  • Prosopagnosia / surgery
  • Seizures / diagnosis*
  • Seizures / etiology
  • Seizures / physiopathology
  • Seizures / surgery
  • Temporal Lobe / diagnostic imaging*
  • Temporal Lobe / physiopathology
  • Treatment Outcome