Autologous fat grafting with stem cell transplantation in an exstrophic patient. A case

J Pediatr Urol. 2021 Feb;17(1):119-121. doi: 10.1016/j.jpurol.2020.12.017. Epub 2020 Dec 31.

Abstract

Introduction: Lipofilling has been used in plastic surgery for breast reconstruction and treatment of burns. Carrying out minimally invasive techniques would allow treatment of hypertrophic scars and depressed suprapubic area in exstrophic patients to improve their aesthetic appearance.

Material and methods: This video presents the case of a female 16 year old patient with bladder exstrophy, who initially had an urinary reconstruction with ureterosigmoidostomy and posteriorly bladder augmentation and Mitrofanoff, with hypertrophic scars and depressed abdominal wall in suprapubic area. We present this procedure for autologous fat grafting with stem cells in the abdominal area.

Results: The lipofilling procedure was carried out successfully, without intraoperative complications in 120 min. The liposuction was 250 cc and 80 cc was used for injection, achieving the improvement of the aesthetic appearance of the scars in a short time. The imaging control was follow up with abdominal wall ultrasound, three months later, increasing its thickness by 42%.

Conclusion: The autologous fat grafting with stem cells is a safe and feasible procedure in the exstrophic population, with excellent aesthetic results, but we need long term follow ups to determine how long the effect of fat grafting remains.

Keywords: Exstrophic bladder; Stem cell; Tissue engineering.

Publication types

  • Case Reports
  • Video-Audio Media

MeSH terms

  • Adipose Tissue
  • Adolescent
  • Bladder Exstrophy* / surgery
  • Female
  • Humans
  • Mammaplasty*
  • Stem Cell Transplantation
  • Transplantation, Autologous